Utrecht University > Biology > Bioinformatics > Group members > Gabino F. Sanchez Perez

Personalia

Gabino F. Sanchez Perez
Name Gabino F. Sanchez Perez
Position Postdoc
Research topics Plant Stem Cells
Evolutionary Systems Biology
Affiliations Bioinformatics group, Utrecht University
Address Padualaan 8
3584 CH Utrecht
the Netherlands
Location Room Z532
Phone +31 30 253 3004
Fax +31 30 251 3655
Email g.f.sanchezperez(at)uu(dot)nl

Research

Unlike animals, plants are constantly generating tissues and organs from two apical meristems throughout lifetime. The maintenance of these functional meristems requires delicate coordination between the loss of stem cells through differentiation and the replacement of these cells through division. Root and shoot organizers seem to control stem cell number by an equivalent mechanism and we work under the hypothesis that analogies/homologies between roots and shoots underlie against variations of an ancestral gene network. Our goal is to characterize the mechanism of action of the different master regulators in both meristems, integrating different sources of information, unravelling the gene regulatory network controlled by these transcription factors.

I am also developing methods to understand amino acid adaptation in extremophiles.

Publications

Schluepmann H, Berke L, Sanchez-Perez GF. (2011) Metabolism control over growth: a case for trehalose-6-phosphate in plants. J Exp Bot  
Prasad K, Grigg SP, Barkoulas M, Yadav RK, Sanchez-Perez GF, Pinon V, Blilou I, Hofhuis H, Dhonukshe P, Galinha C, Mahonen AP, Muller WH, Raman S, Verkleij AJ, Snel B, Reddy GV, Tsiantis M, Scheres B. (2011) Arabidopsis PLETHORA transcription factors control phyllotaxis. Curr Biol  
Garrido F, Estrela S, Alves C, Sanchez-Perez GF, Sillero A, Pajares MA.(2011) Refolding and characterization of methionine adenosyltransferase from Euglena gracilis. Protein Expr Purif  
Ten Hove CA, de Jong M, Lapin D, Andel A, Sanchez-Perez GF, Tarutani Y, Suzuki Y, Heidstra R, van den Ackerveken G. (2011) Trans-Repression of gene activity upstream of T-DNA Tagged RLK902 links Arabidopsis root growth inhibition and downy mildew resistance. PLOS ONE  
Ten Hove CA, Bochdanovits Z, Jansweijer VM, Koning FG, Berke L, Sanchez-Perez GF, Scheres B, Heidstra R. (2011) Probing the roles of LRR RLK genes in Arabidopsis thaliana roots using a custom T-DNA insertion set. Plant Mol Biol  
Bennett T, van den Toorn A, Sanchez-Perez GF, Campilho A, Willemsen V, Snel B, Scheres B. (2010) SOMBRERO, BEARSKIN1, and BEARSKIN2 regulate root cap maturation in Arabidopsis. Plant Cell  
Calis JJA, Sanchez-Perez GF, Kesmir C (2010). MHC class I molecules exploit the low G+C content of pathogen genomes for enhanced presentation. Eur J Immunol.  
Kamikawa R, Sanchez-Perez GF, Sako Y, Roger AJ, Inagaki Y. (2009). Expanded phylogenies of canonical and non-canonical types of methionine adenosyltransferase reveal a complex history of these gene families in eukaryotes. Mol Phylogenet Evol  
Sanchez-Perez GF, Hampl V, Simpson AG, Roger AJ. (2008). A new divergent type of eukaryotic methionine adenosyltransferase is present in multiple distantly related secondary algal lineages. J Eukaryot Microbiol.  
Sanchez-Perez G, Mira A, Nyiro G, Pasic L, Rodriguez-Valera F. (2008). Adapting to environmental changes using specialized paralogs. Trends Genet.  
Mongodin EF, Nelson KE, Daugherty S, Deboy RT, Wister J, Khouri H, Weidman J, Walsh DA, Papke RT, Sanchez Perez G, Sharma AK, NesbÝ CL, MacLeod D, Bapteste E, Doolittle WF, Charlebois RL, Legault B, Rodriguez-Valera F. (2005). The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea. PNAS.  
Sanchez-Perez GF, Bautista JM, Pajares MA. (2004). Methionine adenosyltransferase as a useful molecular systematics tool revealed by phylogenetic and structural analyses. J Mol Biol.  
Sanchez-Perez GF, Gasset M, Calvete JJ, Pajares MA. (2003). Role of an intrasubunit disulfide in the association state of the cytosolic homo-oligomer methionine adenosyltransferase. J Biol Chem.  

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